Phosphatidic acid (PA) is the simplest glycerophospholipid naturally occurring in living
organisms, and even though its content among other cellular lipids is minor, it is drawing
more and more attention due to its multiple biological functions. PA is a precursor for other
phospholipids, acts as a lipid second messenger and, due to its structural properties, is also
a modulator of membrane shape. Although much is known about interaction of PA with its
effectors, the molecular mechanisms remain unresolved to a large degree. Throughout …